The research team used four quadrants prospective evaluation method of endoscopic biopsy for 322 patients in the biopsy and histological analysis by flow cytometry. Each of these patients experienced at least one follow-up, 41 cases were detected, 34 cases of cancer in five years.
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Researchers in July of the American Journal of Gastroenterology (up) says: Gastroenterology, think “, that the results are not aneuploidy, no 4 – times of the chromosome diagnosis is unknown or low-grade atypical patient for five years, but have severe dysplasia 0% aneuploidy or 4 times of severe dysplasia patients increased chromosome 28%. This means that the risk factors may be delayed again after 5 years for any patient “.
Dr Reid said: “There are four times more chromosomes and aneuploid chromosomes and very atypical patients with severe dysplasia or 5 years, 43% and 59%, 56% flow cytometric detection of abnormal worth more frequently follow-up.”
Four quadrant endoscopic biopsy method has advantages over conventional methods, usually endoscopic biopsy samples taken from experts more than 4 pieces, this study of 322 patients received huge amount of biopsy samples, half for the histological evidence for the semi-flow cytometric detection. Four-quadrant endoscopic biopsy method by aneuploidy, four times more chromosomes and very atypical index in 5 years to detect up to 34 cancer patients, and two-quadrant method to 82% seen only aneuploid, 76 percent of patients, chromosome aneuploidy and / or 4 – fold increase of chromosome patients and 59 percent of patients with atypical squamous esophageal mucosa height.
Normal coating, such as local mucosal epithelium was squamous, called Barrett’s esophagus. Early in 1805, Schmidt in his first essays ectopic gastric mucosa in the esophagus island described, but not the cause for the doctor visit. By 1950, Barrett Barrett) in Great Britain (the surgical magazine reported lower esophageal mucosal coating epithelial lesions and, in 1957 and made a detailed description of the medical treatment, causing the esophagus. Then, says the author of columnar mucosa, like Barrett’s esophagus squamous the esophagus. Hospital for Barrett’s esophagus) is not uncommon.barrett, higher rate (1.4% ~ clans report), an average of 16.3% respectively.
Together we concern the esophagus, make life more beautiful.
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- What Is Barrett’s Esophagus?
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